KYIV, UKRAINE • Russian missiles hit residential areas in an eastern Ukrainian city Thursday for the second time in 24 hours, while European Union officials held talks with the government in Kyiv as the war with Russia approaches its one-year milestone.

The latest strikes in Kramatorsk came as rescue crews searched for survivors in the rubble of an apartment building hit late Wednesday by a Russian missile that killed at least three people and wounded 21 others. At least one more victim was thought to be under the debris, Ukraine’s presidential office said.

“Kramatorsk again shattered by explosions — the Russians made two more rocket strikes,” regional governor Pavlo Kyrylenko wrote in a Telegram post.

He said at least five civilians were wounded in the latest strikes, which hit residential buildings as well as a children’s clinic and a school in the heart of the city.

Kramatorsk Mayor Oleksandr Honcharenko urged residents to stay in shelters.

Kramatorsk is a major hub for the Ukrainian military in the east.