MIAMI • When Florida Gov. Ron Desantis announced his candidacy for president Wednesday, confirming years of speculation, he made a speech to the Twitter-verse that hit on themes most Republicans would get behind: He would build a border wall, end inflation and, most importantly, he would beat President Joe Biden in November 2024.

But Desantis followed that standard campaign rhetoric with a wide-ranging discussion that touched on a number of more niche issues. Along with billionaire Elon Musk and a supporting cast of other sympathetic conservatives, Desantis delved into the concerns of a certain kind of plugged-in Republican: tech censorship and cryptocurrency regulation.

“As president, we’ll protect the ability to do things like bitcoin,” Desantis said at one point.

The scattered nature of his audio-only Twitter launch event highlighted a broader challenge for Desantis as he moves forward with his presidential campaign: How can he piece together a winning coalition of Republican voters?

Young and old, white collar and blue, Never Trump and Ultra MAGA — Desantis will likely need support from a group of voters with wide-ranging priorities to best former President Donald Trump for the GOP nomination.

He’ll also need to walk a numerical tightrope. Trump leads Desantis by an average of more than 30 points in national polls, according to Realclearpolitics. Three pollsters interviewed by the Tampa Bay Times estimated that at least one-third of GOP primary voters are unshakable supporters of Trump. Desantis has essentially no shot at attracting that bloc, they said.

“That’s an awfully big base to start with in a multicandidate field,” said Matthew Shelter, a partner at the Beacon Research political polling firm.

Beacon has found that roughly 40% of GOP voters consider themselves supporters of Trump more than they consider themselves supporters of the Republican Party, Shelter said.

When fundraisers from around the country gathered at the Four Seasons Hotel Miami earlier this week to give Desantis a jolt of money — he raised $8.2 million in the first 24 hours, according to the campaign — they were first briefed by the governor’s top pollster and other staff about their potential path to victory.

The focus was not on peeling away anyone from Trump’s stronghold. Instead, Desantis’ camp has been strategizing about how best to capture the rest of the voters.

Evangelical voters are a major part of this strategy. Desantis’ backers believe they will be swayed by his anti-woke crusades against LGBTQ+ inclusive school lessons, as well as his recent signing of a bill banning most abortions after six weeks of pregnancy.

On Monday night, Desantis spoke at the National Religious Broadcasters convention, billed as “the world’s largest gathering of Christian communicators.”

“The people who are in power now do not like people of faith, and so we have to get this government under control,” DeSantis told them.

Desantis’ team has also touted its 2022 success winning over female voters — a bloc Trump lost in the 2016 and 2020 general elections. And Desantis has historically done well with college-educated Republicans.

“You need to get to 50% plus one of Republican voters, and I think that Desantis has the ability to gain support from every constituency in the Republican Party,” said lobbyist Justin Sayfie, who was one of the people raising money for Desantis in Miami.